It's 1969, and holed up in a grimy tenement building in New York's Lower East Side is a travelling psychic who claims to be able to tell anyone the date they will die. The four Gold children, too young for what they're about to hear, sneak out to learn their fortunes.

Over the years that follow, the siblings must choose how to live with the prophecies the fortune-teller gave them that day. Will they accept, ignore, cheat or defy them? Golden-boy Simon escapes to San Francisco, searching for love; dreamy Klara becomes a Las Vegas magician; eldest son Daniel tries to control fate as an army doctor after 9/11; and bookish Varya looks to science for the answers she craves.